There’s also a 14-day free trial so you can try it out, risk-free. In terms of pricing, you can use it on a monthly or yearly billing cycle, with two tiers depending on your needs. Once someone replies, your conversations will show up inside QuickMail so you won’t need to switch between QuickMail and your inbox all day. You can add as many email follow-up steps as you need to your campaigns and even send campaigns from multiple inboxes at once to improve deliverability. When writing your templates you can use “attributes” inside the email editor to add personalized mail merge fields, which will update automatically for every recipient on your email list. After importing your prospect list from a CSV or automatically importing it from a Google Sheet, you can create a campaign and start writing your email templates. QuickMail is a mail merge platform made for teams sending cold email at scale. Install Right Inbox from the Google Chrome Store today. It gives you everything you need for a successful email outreach campaign. It goes from $7.95/month to $14.95/month depending on the plan. Sequences – You can create email sequences that automatically send follow-ups to recipients who haven’t replied to your email.Įmail Tracking – Right Inbox notifies you if your recipient has read the email, how many times, and if they’ve clicked on any link.Įmail Scheduler – With the email scheduler, you can set Right Inbox to send emails when your recipients are most likely to open their Gmail app. The software has multiple features that work in conjunction with the mail merge feature. Like any other mail merge tool, the goal is to help you send as many emails as possible at once without losing personalization for each recipient.Īs a result, you can use Right Inbox to update your customers on an upcoming deal, mass email journalists for a PR campaign, or send updates about new additions in your business. Right Inbox offers mail merge and other email productivity features to more than 250,000 professionals.
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Note: Local time in these time zones changes when Daylight Saving Time begins and ends. The well-maintained grounds are home to many different animals, located across four trails on 125 acres. For example, Mountain Time (MT) refers to Mountain Standard Time (MST) or Mountain Daylight Time (MDT), depending on which is currently in use. Time in Phoenix AZ, United States Time now in Phoenix, Arizona, United States State: Arizona Phoenix 2:32:50 AM GMT -07:00 Time zone: MST (GMT -07:00) USA clocks are now on: Daylight Saving Time Daylight Saving Time ends: Novem02:00 local time. Clifford / Shutterstock The Phoenix Zoo in Arizona’s Papago Park is a fantastic place to head to if you’re an animal lover, or if you’re coming with kids. Phoenix hour difference from GMT: -07:00. United States is not currently observing Daylight Saving Time (DST). Phoenix’s time zone: UTC -07:00 or MST Current time by city Daylight saving time (DST) changes in Phoenix No daylight saving time (DST) in Phoenix. The time zones in the contiguous United States are often referred to by their generic name, without making a difference between standard time and DST designations. Convert time in Phoenix, Arizona (AZ), United States to other locations. Generalized Time Zone in Arizona Time Zone Abbreviation & Name Because MST and PDT have the same UTC offset of minus 7 hours (UTC-7), Arizona has the same local time as neighboring states California and Nevada during the summer season. Some courses may be offered over time periods for which these dates are not. There is a common misconception that Arizona is on Pacific Daylight Time (PDT) during the summer and on Mountain Standard Time (MST) during the winter. Below are the current and future academic calendars for Phoenix College. However, because the Navajo Nation observes Daylight Saving Time (DST), the corresponding DST designation, Mountain Daylight Time (MDT) is also listed here. Most of Arizona observes Mountain Standard Time (MST) all year. Time Zones Currently Being Used in Arizona Offset When are flight tickets from Phoenix (PHX) to New York (NYC) the cheapest How much are flights from Phoenix to New York How long does it take to fly from. Business Date to Date (exclude holidays). If you’re looking for a family-friendly monitor that can do a little bit of everything, ViewSonic’s model has you covered. Why you should buy it: This monitor has dual 3W speakers, 1080p resolution, a wide variety of ports, and eye comfort features - all of which work well together to support a productive online learning experience or a fun family movie or game night. Who is the ViewSonic VX2476-SMHD for? It's for families or students who take online classes. However, for internal speakers, this setup is hard to beat! While the speaker sound is solid and great for watching shows with others, it’s not going to match the quality and immersion of something like a great gaming headset. Ports for the Tuf VG27AQL1A include DisplayPort 1.2 and two HDMI 2.0 connections. The 27-inch monitor also boasts an impressive 1-ms response time, features to optimize eye comfort, and a shadow-boost feature that improves image quality in dark or bright scenes. It has excellent gaming features like a WQHD, 2560 x 1440 resolution, up to a 170Hz refresh rate for smooth action, and G-Sync compatibility for your Nvidia GPU. If that sounds like you, start with this Asus pick. Many users are interested in a gaming-capable monitor that can also supply its own sound when necessary. Why you should buy it: With built-in speakers and a speedy response time, it's a solid pick for gamers who also want to host movie nights with friends. Who is the Asus Tuf VG27AQL1A for? Gamers who want built-in speakers. Scenario with this thing right over here. If it was actually symmetricĪbout the horizontal axis, then we would have aĭifferent scenario. Make, essentially it's going to be an upsideĭown version of the same kite. Our body is divided into two symmetrical parts, right and left. In ourselves: we have a right hand and a left hand, a right ear, and a left ear, and each pair is symmetrical. The image reflected is symmetrical to the real image. Now let's think about thisįigure right over here. Symmetry is all around us: In a mirror or the reflection on the water’s surface. If a polygon is irregular, chances are there will be less lines of symmetry. To the center of the figure, and then go thatĭistance again, you end up in a place where It does change, but depends more on if the polygon is regular or not. Let's say the center of theįigure is right around here. Or I should say, it willĪround its center. So I think this one willīe unchanged by rotation. Same distance again, you would to get to that point. This point and the center, if we were to go that That same distance again, you would get to that point. If rotational symmetry, identifying all angels of rotation as well as the order of rotational symmetry. If reflectional symmetry, draw the lines of reflection. In fact the arms of sea stars and other radiate organisms are called rays. Radial indicates a circular configurationsomething with a radius or rays. Symmetry means a balanced or proportional arrangement of parts. The symmetry of shapes can be identified whether it is a line of symmetry, reflection or rotational based on the appearance of the shape. What type of body symmetry does a sea star have explain why Pentamerism is a type of radial symmetry. If we change the combination’s order, it will not alter the output of the glide reflection. If rotational symmetry, identifying all angels of rotation as well as the order of rotational symmetry. A glide reflection is commutative in nature. Point and the center, if we were to keep going If reflectional symmetry, draw the lines of reflection. Think about its center where my cursor is right And then if rotate it 180ĭegrees, you go over here. Rotate it 90 degrees, you would get over here. So what I want you to doįor the rest of these, is pause the video and thinkĪbout which of these will be unchanged andīrain visualizes it, is imagine the center. I have my base is shortĪnd my top is long. What happens when it's rotated by 180 degrees. Trapezoid right over here? Let's think about Square is unchanged by a 180-degree rotation. Unbounded shapes have a richer range of symmetries, as seen in friezes and wallpaper patterns. Finite groups of rigid motions fall into several categories: cyclic groups, dihedral groups, orthogonal groups, and special orthogonal groups. So we're going to rotateĪround the center. The four main types of this symmetry are translation, rotation, reflection, and glide reflection. And we're going to rotateĪround its center 180 degrees. One of these copies and rotate it 180 degrees. Were to rotate it 180 degrees? So let's do two Which of these figures are going to be unchanged if I This app is for existing Peek Pro partners. Take and send photos directly from the app to create lasting memories for your guests Reschedule or cancel existing bookings and issue refunds from anywhere View assigned schedules and manifests to keep your staff up to date on arrivalsĬheck in guests in seconds with QR Codes, and sign digital waivers on the spot Use Peek Checkout as a POS to quickly take walk-up bookings With Peek Pro, you will find it easier to: Get more bookings. Manage and redeem memberships from your most loyal customers Peek Pro is an online reservation system with a focus on making life easier. The software helps activity operators by providing their websites with an online booking management engine and centrally manages online, offline and third-party reservations. Send emails and texts directly to customers to share updates and booking details Booking Software for Experience Providers Write Review What is Peek Pro and how does it work Peek Pro is a cloud-based solution for tour and activity operators of all sizes. A customizable online booking process that is easy to use, mobile-friendly, and fast will give your customers the best possible experience. Maximize revenue and customer satisfaction at every stage of the journey. If the customer is purchasing any add-ons, please click the View All button below the ticket selection. Peek is the other large company we are focusing on here, and they were founded in 2012 by former investment banker Ruzwana Bashir. It can help you do various tasks like manage reservations, handle bookings, and even conduct marketing efforts, giving you more time for other important duties within the company. The software also allows users to create customized. Drive online and in-person bookings, manage payments, availability, reporting, and much more - all in one place. Click on the button in the upper right corner. Booking software allows tour companies to handle their day-to-day processes in a more seamless and efficient way. Peek Pro is a cloud-based solution for tour and activity operators of all sizes. to take online bookings and manage their business GET STARTED Simple to Use. Keep staff happy with the ability to collect tips at any time Peek Pro is an all in one suite that makes it easy to sell more tours, activities, or rentals. How to Create a Manual Booking: You can make manual bookings from any page within Peek Pro. No signal? No problem! Any changes made will sync across devices as soon as you’re back online.Ĭreate customized dashboards to quickly sell activities, rentals, and merchandise any way you want Every step of the customer-facing booking process is optimized to drive conversions and. Whether on iPad or mobile, the Peek Pro app lets you maximize revenue, streamline staff operations and get a real-time view of your daily outlook. Peek Pro is a reservations system built with and for tour operators. Peek Pro’s mobile app is designed to help you quickly manage your business on the go from anywhere. Without unpausing, recall your merchant from Valencia. Then grant the Burghers the 'Exclusive Trade Rights' privilege, that grants 3 immediate mercantilism. Send a merchant to collect trade in Valencia. Move Aragon's capital (or main trade city, if you have Wealth of Nations) out of the Valencia trade node. AchievementĮasy to do as Aragon within 1-2 years. VE = Very Easy, E = Easy, M = Medium, H = Hard, VH = Very Hard, I = Insane, UC = Uncategorized. DI This column contains a difficulty index assigned by wiki editors. Achievements cannot be earned prior to the version they were added in (and no lower than 1.6). Ver This column indicates in which version of the game a certain achievement was added. The icon means it can also be achieved with custom nations those without this icon can't be achieved if any custom nations exist, even if played by AI (The exceptions are The Ostenders which allows a custom nation and Copium Wars which allows multiple custom nations on the map, but don't allow playing as that nation, because the player has to start as Austria/ Ming). This column denotes achievements which can't be completed without the use of DLC mechanics (currently 106 out of 354). Notes This column lists helpful short tips/strategies. Fulfilling the requirements will un-hide the achievement. "Eat your greens", "Basque in Glory", "An Unlikely Candidate" etc.). Note that the in-game logic for showing an achievement in the list sometimes erroneously contains an extra "Playing as " and as such some achievements which are still possible may be hidden from the player upon forming another nation (eg. Completion requirements This column lists the conditions which will award the achievement if they are fulfilled in a campaign which already fulfilled the “starting conditions” at the start of the campaign. Starting conditions This column contains the conditions which have to be fulfilled at the start of the campaign. List of achievements Achievement This column shows the icon, name (optional with a link to a guide) and the description of the achievement. E.g., Azur semé de lis or can be earned in 1.11, but Big Blue Blob cannot, since it was only added in 1.12. These are noted in the Starting conditions column of the list.Īchievements can be earned while playing older versions of the game (1.6 and above) as long as the given achievement was present in that version. Most achievements have Starting conditions which have to be fulfilled when starting the campaign before any player input.Some achievements don't allow the player to play as a released vassal and this also prohibits playing as a released colonial nation and switching to a different country in an event(forming countries via event is allowed).Most achievements don't allow any custom nations on the map(exceptions are noted in the list).All but 4 achievements require that the game was started at 11 November 1444(exceptions are noted in the list).Nations must be set to “Normal setup” or “Historical setup”.Province Tax and Manpower must be set to “Normal values”.Limited country forming must be set to “Yes”.Lucky nations must be set to “Historical”.Difficulty must be set to “Normal” or higher.Most graphical, interface or music mods don't alter the checksum and thus are allowed. So no gameplay altering mod may be active and the game files must not be corrupted or modified in a different way. The game files must have the correct checksum for the game version.To gain achievements one needs to play in ironman and also obey the following requirements(ironman itself is still possible even when not fulfilling these requirements): The below list groups the various achievements by a difficulty level as assessed by the wiki editors (uncategorized - UC - achievements haven't been assessed yet). taking all of Asia's grassland as Kale before the age of absolutism). signing a royal marriage with another country), while some are extremely difficult (e.g. The difficulty of each achievement varies some achievements are very easy (e.g. It is possible to see the achievements sorted by the percentage of users that managed to complete each achievement by going to the game's global achievements at Steam (for more precise numbers one can use the Steam web API). Achievements have no in-game effects the achievement just pops up in-game and then added to the player's Steam profile. Please help with verifying or updating older sections of this article.Īt least some were last verified for version 1.34.įor tips and tricks on how to complete an achievement, see the achievements category.ĮU4 has 354 different achievements, all using the Steam achievements mechanics. 17 – 20 Furthermore, particular tet/dox systems have been found to be leaky in vivo 21 (although headway has been made in this regard 22), and high levels of tetracyclines have been suggested to disrupt mitochondrial homeostasis. Secondly, mouse in vivo tet/dox reversibility experiments typically use a 1- to 2-week induction “on” period for full activation, followed by a 1- to 3-week washout “off” period for full reversibility. Firstly, tet/dox systems regulate gene expression at the transcriptional level, requiring subsequent protein translation, which takes additional processing time. While this inducible system has been validated and utilized successfully in the mouse eye, 14 – 16 it is not an ideal approach for reversibly and repeatedly regulating protein abundance. The most commonly used conditional gene therapy approach relies on the tetracycline/doxycycline (tet/dox)-inducible system. Therefore, there is an urgent need to develop and validate a conditional and reversible therapeutic strategy that allows for experimental control of the timing and extent of production of a protein of interest (e.g., a stress-responsive transcription factor) in the eye. 8 – 13 However, the technical capability to regulate these signaling pathways in a physiological context (i.e., conditional sinusoidal expression) and under spatial and temporal control is lacking. 5 – 7 These risks are especially problematic when attempting to control cellular signaling pathways responsible for promoting protein homeostasis such as the unfolded protein response, oxidative stress response, inflammation and autophagy, all of which are incontrovertibility linked to incurable eye diseases. 4 While appropriate in certain contexts, such as for restoring genes that are incapacitated by loss-of-function mutations or premature stop codons, constitutive ectopic gene expression does bear the potential risk of unanticipated side effects due to sustained, elevated expression in a nonphysiologic (and potentially disadvantageous) manner. This DHFR-based conditional system is a rapid, efficient, and reversible tool to effectively control protein expression in the retina.Ĭonventional gene therapy approaches utilize constitutive gene expression to combat ocular diseases such as Leber's congenital amaurosis (LCA), 1 choroideremia, 2 MERTK-associated retinitis pigmentosa, 3 amongst others. Long-term TMP treatment had no impact on retina function/structure and had no effect on >99.9% of tested genes. Stabilization was completely and repeatedly reversible following removal/addition of TMP in all regimens. Oral gavage and TMP eye drops stabilized DHFR.YFP as quickly as 6 hours, whereas continuous TMP drinking water could stabilize DHFR.YFP for ≥3 months. TMP achieved ocular concentrations of ∼13.6 μM (oral gavage), ∼331 nM (drinking water), and ∼636 nM (eye drops). Without TMP, DHFR.YFP was efficiently degraded in the retina. Visual acuity, response to light stimulus, retinal structure, and gene expression were evaluated after long-term (3 months) TMP treatment. Protein abundance was measured by fundus fluorescence imaging and western blotting. Ocular TMP levels post treatment were quantified by LC-MS/MS. TMP or vehicle was administered to mice via oral gavage, drinking water, or eye drops. We intravitreally injected wild-type C57BL6/J mice with an adeno-associated vector (rAAV2/2) constitutively expressing separate fluorescent reporters: DHFR fused to yellow fluorescent protein (DHFR.YFP) and mCherry. Accordingly, we explored whether protein abundance in the mouse retina could be effectively controlled using a destabilizing Escherichia coli dihydrofolate reductase (DHFR) domain whose stability is dependent on the small molecule, trimethoprim (TMP). Temporal and reversible control of protein expression in vivo is a central goal for many gene therapies, especially for strategies involving proteins that are detrimental to physiology if constitutively expressed. Patients who’ve had one or more pregnancy or who’ve lost large amounts of weight will often find they have excess flaccid and sagging skin in their stomach area which won’t budge through diet and exercise alone. Having a firm, flat stomach can have a huge impact on the way patients feel about themselves. By removing excess fat and loose skin from a patient’s abdomen and tightening the stomach muscles their abdominal contours are improved. What are the benefits of a tummy tuck?Ī tummy tuck is used to reshape the waist and create a slimmer, smoother and tighter abdominal area. It results in a smaller scar and is recommended for patients who have a less significant amount of excess abdominal skin and those who are experiencing minor skin sagginess.Ī full tummy tuck would be performed on patients with more excess skin and who require additional muscle tightening.Ī tummy tuck is often performed in conjunction with liposuction, a procedure also to remove unwanted body fat, for those looking to achieve a slimmer waistline. A mini tummy tuck is a quicker and less invasive procedure than the full abdominoplasty. Patients can choose from a full abdominoplasty or a mini abdominoplasty. It is performed for both cosmetic and health reasons. Tummy tuck surgery, also known as an abdominoplasty procedure, refers to the removal of excess fatty tissue and skin from around the waist and the tightening of the muscles in the abdominal wall. So, go for a quality lock that works as intended every time, including strength and durability. It should never unlock when you try to lock it and vice versa. Smart locks come in all shapes, sizes, and features, so how do you choose the right one? Let’s discuss what you should look for.įirst, you need to prioritize how well the lock works in terms of safety. It adds convenience to your life and helps to secure your home. Installing smart locks on your doors can remove the need to carry a key around. What to Look for in a Smart Lock in 2023 Best Smart Lock Overall: August Wi-Fi Smart Lock Best Budget Smart Lock: Hornbill 7-in-1 Smart Door Lock Best Smart Lock for Airbnb: Yale Assure Lock 2 Best Smart Lock for Alexa: August Smart Lock Best Smart Lock for HomeKit: Kwikset Premis Smart Lock Best Smart Lock for Google Home: Google Nest x Yale Smart Lock Frequently Asked Questions Update, : We’ve reviewed our recommendations and have replaced our best for Airbnb pick with the Yale Assure Lock 2. ✗ Doesn't integrate as well with other smart home products ✗ Doesn't support other voice assistants except HomeKit ✓ Control from anywhere with Nest Connect ✓ Seamless integration with Google Home and Nest products ✓ Option to automatically lock and unlock door ✓ Use Siri from anywhere with a HomeKit hub ✓ Option to automatically lock and unlock Google and Nest teamed up to create this innovative Nest x Yale Smart Lock to double down on your home security. You can use Siri from anywhere to control and monitor the lock. Kwikset's Premis Smart Lock is exclusively designed for Apple HomeKit users. The August Smart Lock works perfectly with Alexa so that you can use voice commands to control it from anywhere. It's perfect for indoor or outdoor use, even in areas that see wide temperature and weather ranges.ĭespite lackluster battery life and an expensive price tag, the Yale Assure Lock 2 was practically designed for rental properties, with the ability to generate temporary passwords and check in on the status of your front door This budget smart lock is well-constructed and feature-rich. Don't know which smart lock to go for? The August Wi-Fi lock is affordable and comes with many premium features such as two-factor authentication. However, if we’re talking about image quality, there is definitely a difference between the 50MP GFX50 II and the 40MP X-T5. At more than twice the price and almost double the weight, is the GFX kit twice as good as the X Series kit? If we’re only talking about the resolution, the answer is obviously no. In addition, the weight of the X-T5 + XF10-24mmF4 is only 42g heavier than just the body of the GFX50S II. You can buy an X-T5 and the XF10-24mm lens for just over the price of just the GF20-35mmF4 lens on its own. The biggest difference is size, weight and price. However, the point of this comparison is to see if there is still a place in the GFX ecosystem for a 50MP camera if the X Series has a 40MP sensor. In addition, due to the huge sensor-size difference, there are going to be differences in depth-of-field at the same aperture, ISO performance, rolling shutter and aspect ratio. The older XF10-24mm zoom lens is not optimal for the new 40MP sensor, while the GF20-35mmF4 R WR can resolve beyond 100MP. The first thing I want to mention is that this isn’t a clinical test between these two cameras and lenses. This got me thinking: is there any reason to buy a 50MP digital medium format camera anymore? I decided to answer that question for myself by asking Fujifilm Canada to send me the GFX50S II and the GF20-35mmF4 R WR for me to test against the X-T5 and XF10-24mmF4 R OIS. Moreover, I was accustomed to using these higher-megapixel cameras and getting the X-T5 scratched that itch for me. I also review Leica camera gear I’ve been using the 40MP Leica M10-R for the past few months, and I love the 47MP Leica Q2 and SL2. I know I didn’t need all that extra resolution but it was fun to have in a pinch. I was content with 26MP for the past few years, but I’ve also had the opportunity to play with Fujifilm’s 50MP and 100MP medium format cameras, and I was jealous. For years I committed myself to the X Series for my entire digital workflow for both video and stills. When Fujifilm announced the 40MP X-H2 in 2022, I was relieved. |
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